Crosstalk and Integration of Membrane Trafficking Pathways

Crosstalk and Integration of Membrane Trafficking Pathways
InTeO | 2012 | ISBN: 9535105152 9789535105152 | 256 pages | PDF | 8 MB

A concept that has clearly emerged in the last decade is that each membrane pathway does not represent a close system, but is fully integrated with all the other trafficking pathways. The aim of this book is to provide a general overview of the extent of this crosstalk.
Membrane traffic is a broad field that studies the complex exchange of membranes that occurs inside the cell. Protein, lipids and other molecules traffic among intracellular organelles, and are delivered to, or transported from the cell surface by virtue of membranous carriers generally referred as "transport intermediates". These carriers have different shapes and sizes, and their biogenesis, modality of transport, and delivery to the final destination are regulated by a multitude of very complex molecular machineries.
Contents
1 Semi-Intact Cell Systems - Application to the Analysis of Membrane Trafficking Between the Endoplasmic Reticulum and the Golgi Apparatus and of Cell Cycle-Dependent Changes in the Morphology of These Organelles
2 Mophogenesis and Dynamics of Post-Golgi Transport Carriers
3 Phosphatidylinositol Bisphosphate Mediated Sorting of Secretory Granule Cargo
4 Molecular Machinery Regulating Exocytosis
5 At the Intersection of the Pathways for Exocytosis and Autophagy
6 Peroxicretion. a Novel Tool for Engineering Membrane Trafficking
7 Endocytosis and Exocytosis in Signal Transduction and in Cell Migration
8 Making the Final Cut - The Role of Endosomes During Mitotic Cell Division
9 Enzymology and Regulation ofArfGAPs and ArfGEFs
10 Metal Ion Homeostasis Mediated by NRAMP Transporters in Plant Cells - Focused on Increased Resistance to Iron and Cadmium Ion
11 Analysis of SNARE-Mediated Exocytosis Using a Cell Fusion Assay